Function GetCurrentPrinterHandle: THandle;
      Const
        Defaults: TPrinterDefaults = (
          pDatatype : nil;
          pDevMode  : nil;
          DesiredAccess : PRINTER_ACCESS_USE or PRINTER_ACCESS_ADMINISTER
    );
      Var
        Device, Driver, Port : array[0..255] of char;
        hDeviceMode: THandle;
      Begin { GetCurrentPrinterHandle }
        Printer.GetPrinter(Device, Driver, Port, hDeviceMode);
        If not OpenPrinter(@Device, Result, @Defaults) Then
          RaiseLastWin32Error;
      End; { Pega o handle da impressora padrão }

    { mata todos os trabalhos da impressora }
    Procedure PurgeJobsOnCurrentPrinter;
      Var
        hPrinter: THandle;
      Begin
        hPrinter:= GetCurrentPrinterHandle;
        try
          If not WinSpool.SetPrinter( hPrinter, 0, nil,
    PRINTER_CONTROL_PURGE )
          Then
            RaiseLastWin32Error;
        finally
          ClosePrinter( hPrinter );
        end;
      End;

Chame utilizando a procedure, assim…

PurgeJobsOnCurrentPrinter;